Article

Designer Fat Cells: Adipogenic Differentiation of CRISPR-Cas9 Genome-Engineered Induced Pluripotent Stem Cells

2023-10-26

Abstract excerpt

Adipose tissue is an active endocrine organ that can signal bidirectionally to many tissues and organ systems in the body. With obesity, adipose tissue is a source of low-level inflammation that contributes to various co-morbidities and damage to downstream effector tissues. The ability to synthesize genetically engineered adipose tissue could have critical applications in studying adipokine signaling and the use...

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Literature Corpus work: 412c82d6-503e-5a59-bbf2-1fe287fe37ad
DOI: 10.1101/2023.10.26.564206

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