Article

Shared Genetic Architecture and Causal Relationships between Autoimmune Diseases and Venous Thromboembolism: A Large- Scale Cross-Trait Integrative Analysis

2026-06-28

Abstract excerpt

<title>Abstract</title> <p>Background Patients with autoimmune diseases (ADs) have an elevated risk of venous thromboembolism (VTE), but the shared genetic basis remains systematically unexplored. This study aims to elucidate the shared genetic architecture and biological pathways linking ADs to VTE. Methods We conducted a cross-trait genetic analysis using GWAS summary statistics for VTE and 16 ADs. LDSC and H...

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Literature Corpus work: 411ecd7f-0d55-5751-b5cf-927929688565
DOI: 10.21203/rs.3.rs-10074056/v1

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