Article

Metformin Treatment Leads to Increased HIV Transcription and Gene Expression Though Increased CREB Phosphorylation and Recruitment to the HIV LTR Promoter

2023-04-20

Abstract excerpt

Antiretroviral therapy has effectively suppressed HIV infection and replication and prolonged the lifespan of HIV-infected individuals. In the meantime, various complications including type 2 diabetes associated with long-term antiviral therapy have shown steady increases. Metformin has been the front-line anti-hyperglycemic drug of choice and the most widely prescribed medication for the treatment of type 2 diabe...

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Literature Corpus work: 410935e0-c0bb-517a-b3b8-f3acd7528408
DOI: 10.20944/preprints202304.0607.v1

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