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Metformin Treatment Leads to Increased HIV Transcription and Gene Expression through Increased CREB Phosphorylation and Recruitment to the HIV LTR Promoter

2 Aug 2023

Abstract excerpt

Antiretroviral therapy has effectively suppressed HIV infection and replication and prolonged the lifespan of HIV-infected individuals. In the meantime, various complications including type 2 diabetes associated with the long-term antiviral therapy have shown steady increases. Metformin has been the front-line anti-hyperglycemic drug of choice and the most widely prescribed medication for the treatment of type 2...

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PMID: 37450926
DOI: 10.14336/ad.2023.0705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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