Article

Design and in Silico Characterization of a Novel Chimeric P53–SOG1 Fusion Protein for Enhanced Dna Damage Response and Tumor Suppression

2025-11-12

Abstract excerpt

<title>Abstract</title> <p>The tumour suppressor p53 plays an essential role in preserving genomic stability through DNA damage response (DDR) and apoptosis in mammalian systems. By comparison, the transcription factor SOG1 (SUPPRESSOR OF GAMMA RESPONSE 1) is the main regulator of DDR in plants but has similar mechanisms to those occupied by p53 in humans. In this current study, we have designed and through compu...

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Literature Corpus work: 40fcf7ff-9919-5e16-b088-e029fe0f4894
DOI: 10.21203/rs.3.rs-8085560/v1

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Design and in Silico Characterization of a Novel Chimeric P53–SOG1 Fusion Protein for Enhanced Dna Damage Response and Tumor SuppressionDOI 10.21203/rs.3.rs-8085560/v1Read

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