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Article

In silico scanning of structural and functional deleterious nsSNPs in Arabidopsis thaliana's SOG1 protein, using molecular dynamic simulation approaches.

Journal of biomolecular structure & dynamics - 1 Jan 2023

Khan Asif, Waqas Muhammad, Tufail Muhammad, Halim Sobia Ahsan, Murad Waheed, Ahmad Syed Umair, Faheem Muhammad, Uddin Jalal, Khalid Asaad, Abdalla Ashraf N, Khan Ajmal, Al-Harrasi Ahmed

Abstract excerpt

Suppressor of gamma response 1 (SOG1) is a member of the NAC domain family transcription factors of the DNA damage response (DDR) signaling in the plant's genome. SOG1 is directly involved in transcriptional response to DNA damage, cell cycle checkpoints and ATR or ATM-mediated activation of the DNA damage responses and repair functioning in programmed cell death and regulation of end reduplication. Different...

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PMID: 36734218
DOI: 10.1080/07391102.2023.2174187

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