Article
Structural and functional analysis of SGT1-HSP90 core complex required for innate immunity in plants.
EMBO reports - 1 Dec 2008
Kadota Yasuhiro, Amigues Beatrice, Ducassou Lionel, Madaoui Hocine, Ochsenbein Francoise, Guerois Raphaël, Shirasu Ken
Abstract excerpt
SGT1 (Suppressor of G2 allele of skp1), a co-chaperone of HSP90 (Heat-shock protein 90), is required for innate immunity in plants and animals. Unveiling the cross talks between SGT1 and other co-chaperones such as p23, AHA1 (Activator of HSP90 ATPase 1) or RAR1 (Required for Mla12 resistance) is an important step towards understanding the HSP90 machinery. Nuclear magnetic resonance spectroscopy and mutational...
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