Article

Biomarker identification for statin sensitivity of cancer cell lines

2017-11-07

Abstract excerpt

<h4>ABSTRACT</h4> Statins are potent cholesterol reducing drugs that have been shown to reduce tumor cell proliferation in vitro and tumor growth in animal models. Moreover, retrospective human cohort studies demon-strated decreased cancer-specific mortality in patients taking statins. We previously implicated membrane E-cadherin expression as both a marker and mechanism for resistance to atorvastatin-mediated g...

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Literature Corpus work: 40db6ee6-c6da-57a4-810e-03070196ca8f
DOI: 10.1101/215756

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