Article

USP16 Regulates Castration-Resistant Prostate Cancer Cell Proliferation by Deubiquitinating and Stablizing c-Myc

2020-11-24

Abstract excerpt

<h4>Background: </h4> c-Myc, a well-established oncogene, plays an important role in the initiation and progression of various cancers, including prostate cancer. However, its mechanism in cancer cell remains largely unknown and whether there exist a deubiquitinase targeting c-Myc also remains elusive.MethodsBioinformatic analysis and shRNA screening methods were used to identify potential deubiquitinases that cor...

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Literature Corpus work: 40da8e57-512c-53e5-bdeb-15d2cf4e180d
DOI: 10.21203/rs.3.rs-111958/v1

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