Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival

18 May 2018

Abstract excerpt

// Urszula L. McClurg 1, 4, * , Mahsa Azizyan 1, * , Daniel T. Dransfield 2, 5 , Nivedita Namdev 2 , Nay C.T.H. Chit 1 , Sirintra Nakjang 3 and Craig N. Robson 1, * 1 Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK 2 Tokai Pharmaceuticals, 255 State Street, Boston, MA 02109, USA 3 Bioinformatics Support Unit, Faculty of Medical Sciences, Newcastle University,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hormonal and reproductive studies
Share to Prostate Cancer Treatment and Research
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29861848
DOI: 10.18632/oncotarget.25167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survivalPMID 29861848Read ↗

Targeting the signalling pathways regulated by deubiquitinases for prostate cancer therapeuticsSemantic proximity Read ↗

Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptorSemantic proximity Read ↗

Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongationSemantic proximity Read ↗

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and ARSemantic proximity Read ↗

ncRNA-mediated overexpression of ubiquitin-specific proteinase 13 contributes to the progression of prostate cancer via modulating AR signaling, DNA damage repair and immune infiltrationSemantic proximity Read ↗

UBE2J1 is the E2 ubiquitin-conjugating enzyme regulating androgen receptor degradation and antiandrogen resistanceSemantic proximity Read ↗

USP16 regulates castration-resistant prostate cancer cell proliferation by deubiquitinating and stablizing c-MycSemantic proximity Read ↗

USP16 Regulates Castration-Resistant Prostate Cancer Cell Proliferation by Deubiquitinating and Stablizing c-MycSemantic proximity Read ↗

LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance.Semantic proximity Read ↗

USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer ProgressionSemantic proximity Read ↗

The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulatorsSemantic proximity Read ↗

The role of NOP58 in prostate cancer progression through SUMOylation regulation and drug responseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.