Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and AR

1 Mar 2022

Abstract excerpt

Abstract Ovarian tumor (OTU) subfamily deubiquitinases are involved in various cellular processes, such as inflammation, ferroptosis and tumorigenesis; however, their pathological roles in prostate cancer (PCa) remain largely unexplored. In this study, we observed that several OTU members displayed genomic amplification in PCa, among which ovarian tumor deubiquitinase 6A (OTUD6A) amplified in the top around...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35233061
DOI: 10.1038/s42003-022-03133-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and ARPMID 35233061Read ↗

Identification of OTUD6B as a new biomarker for prognosis and immunotherapy by pan-cancer analysisSemantic proximity Read ↗

Deubiquitinase OTUD3: a double-edged sword in immunity and diseaseSemantic proximity Read ↗

Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistanceSemantic proximity Read ↗

The OTUD6B‐LIN28B‐MYC axis determines the proliferative state in multiple myelomaSemantic proximity Read ↗

ncRNA-mediated overexpression of ubiquitin-specific proteinase 13 contributes to the progression of prostate cancer via modulating AR signaling, DNA damage repair and immune infiltrationSemantic proximity Read ↗

VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinomaSemantic proximity Read ↗

VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinomaSemantic proximity Read ↗

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancerSemantic proximity Read ↗

Deubiquitylase OTUD6B stabilizes the mutated pVHL and suppresses cell migration in clear cell renal cell carcinoma.Semantic proximity Read ↗

USP16 Regulates Castration-Resistant Prostate Cancer Cell Proliferation by Deubiquitinating and Stablizing c-MycSemantic proximity Read ↗

OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity.Semantic proximity Read ↗

Targeting deubiquitinase USP28 for cancer therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.