Article

Biologically informed neural network models are robust to spurious interactions via self-pruning

2025-10-27

Abstract excerpt

Computational models of cellular networks hold promise to uncover disease mechanisms and guide therapeutic strategies. Biology-informed neural networks (BINNs) is an emerging approach to create such models by combining the predictive power of deep learning with prior knowledge, a vital aspect of biological research. The architectures of BINN’s enforces a network structure from which mechanism can ideally be inferr...

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Literature Corpus work: 930c876c-f3f5-5da3-877b-9c0a2f338706
DOI: 10.1101/2025.10.24.684155

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