Article

SpaTRACE: Spatiotemporal recurrent auto-encoder for reconstructing signaling and regulatory networks from spatiotemporal transcriptomics data

2025-11-21

Abstract excerpt

Cell–cell communication and gene regulatory programs jointly coordinate cellular behaviors during development, regeneration, and disease. Recent advances in spatial transcriptomics enable measurement of gene expression with spatial context across developmental trajectories, providing new opportunities to study dynamic signaling and regulatory processes. However, most existing methods analyze either ligand–receptor...

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Literature Corpus work: c163f2b7-1ae5-5546-a7ed-90bd7877e065
DOI: 10.1101/2025.11.20.689569

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