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Topological Analysis of Interaction Patterns in Cancer-Specific Gene Regulatory Network: Persistent Homology Approach

2021-02-24

Abstract excerpt

In this study, we investigated cancer cellular networks in the context of gene interactions and their associated patterns in order to recognize the structural features underlying this disease. We aim to propose that the quest of understanding cancer takes us beyond pairwise interactions between genes to a higher-order construction. We characterize the most prominent network deviations in the gene interaction patte...

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Literature Corpus work
407fa733-c169-5776-a37b-e78270fbec3f
DOI
10.21203/rs.3.rs-228335/v1
Open publication

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Topological Analysis of Interaction Patterns in Cancer-Specific Gene Regulatory Network: Persistent Homology ApproachDOI 10.21203/rs.3.rs-228335/v1
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