Article

Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke

2019-07-02

Abstract excerpt

Recent genome-wide association studies in stroke have enabled the generation of genomic risk scores (GRS) but the predictive power of these GRS has been modest in comparison to established stroke risk factors. Here, using a meta-scoring approach, we developed a metaGRS for ischaemic stroke (IS) and analysed this score in the UK Biobank (n=395,393; 3075 IS events by age 75). The metaGRS hazard ratio for IS (1.26, 9...

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Literature Corpus work: 40314e56-c1e9-5c10-966d-a6507f8ae393
DOI: 10.1101/689935

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