Article
Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis.
PloS one - 1 Jan 2011
Meschia James F, Singleton Andrew, Nalls Michael A, Rich Stephen S, Sharma Pankaj, Ferrucci Luigi, Matarin Mar, Hernandez Dena G, Pearce Kerra, Brott Thomas G, Brown Robert D, Hardy John, Worrall Bradford B
Abstract excerpt
INTRODUCTION: Familial aggregation of ischemic stroke derives from shared genetic and environmental factors. We present a meta-analysis of genome-wide association scans (GWAS) from 3 cohorts to identify the contribution of common variants to ischemic stroke risk. METHODS: This study involved 1464 ischemic stroke cases and 1932 controls. Cases were genotyped using the Illumina 610 or 660 genotyping arrays;...
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