Article

Integrated multi-omics analysis identifies novel risk loci for amyotrophic lateral sclerosis in the Chinese population

2024-03-05

Abstract excerpt

<title>Abstract</title> <p>DNA methylation can serve as proxies of (past) exposures and disease progression, as well as provide clues to reveal the pathogenesis of amyotrophic lateral sclerosis (ALS) from the perspective of gene-environment interactions. Here, we conducted an epigenome-wide DNA methylation analysis in peripheral blood cells from 480 cases of ALS (203 had survival data) and 207 health controls of...

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Literature Corpus work: 40046b0b-d8ba-5012-986a-619d31fc77ff
DOI: 10.21203/rs.3.rs-3967132/v1

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