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Epigenome-wide DNA methylation study of whole blood in patients with sporadic amyotrophic lateral sclerosis

20 Jun 2022

Abstract excerpt

BACKGROUND: Epigenetics, and especially DNA methylation, contributes to the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS). This study aimed to investigate the role of DNA methylation in SALS using whole blood of SALS patients. METHODS: In total, 32 SALS patients and 32 healthy controls were enrolled in this study. DNA was isolated from whole blood collected from the participants. DNA methylation...

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PMID: 35853630
DOI: 10.1097/cm9.0000000000002090

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