Article

Temporal regulation of TAK1 to counteract muscular dystrophy

2022-07-23

Abstract excerpt

Muscular dystrophy is a group of genetic neuromuscular disorders that involves severe muscle wasting. Transforming growth factor β-activated kinase 1 (TAK1) is an important signaling protein that regulates cell survival, growth, and inflammation. TAK1 has been recently found to promote myofiber growth in skeletal muscle of adult mice. However, the role of TAK1 in muscle disorders remains poorly understood. In the...

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Literature Corpus work: 3fd8638d-a9cf-5e7c-80cf-269295eb27d6
DOI: 10.1101/2022.07.22.501199

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