Article

IL-1R signaling drives enteric glia-macrophage interactions in colorectal cancer

2023-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Enteric glial cells (EGCs) have been implicated in colorectal cancer (CRC) pathogenesis. However, their precise mechanisms of interaction with the CRC immune cell compartment and pro-tumorigenic role remain unclear. This study aimed to investigate the immunomodulatory effects of EGCs on tumor-associated macrophages (TAMs) and their involvement in CRC progression. Using EGC depletion and suppleme...

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Literature Corpus work: 3fb49f2c-aaca-50a7-b708-b5c09b5da816
DOI: 10.1101/2023.06.01.543246

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