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The Deubiquitin Enzyme USP28 Maintains the Viability of Triple Negative Breast Cancer Cells through Stabilizing the RecQ Family Helicases

2021-07-07

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<title>Abstract</title> <p>Background: Triple-negative breast cancer lacks significant expression of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2. It is the more aggressive and malignant kind of breast cancers and is currently without any effective targeted therapies. <h4>Methods:</h4> We have screened for genes in the ubiquitin-proteasome system that are essential for th...

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Literature Corpus work: 3fb05525-232d-531f-b703-3110a34d2dc9
DOI: 10.21203/rs.3.rs-645209/v1

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