Article

Long-term mouse spinal cord organotypic slice culture as a platform for validating cell transplantation in spinal cord injury

2024-01-29

Abstract excerpt

<h4>ABSTRACT</h4> Spinal cord injury (SCI) is an extremely invalidating condition with a severe physical and psychological impact. Resolutive cures are still lacking, due to its complex pathophysiology. One of the most promising regenerative approaches is based on stem cell transplantation to replace lost tissue and promote functional recovery. This approach should be explored better in vitro and ex vivo for sa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3f983fe7-8c64-502f-a00e-2c0546f6dbcb
DOI: 10.1101/2024.01.29.577615

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Long-term mouse spinal cord organotypic slice culture as a platform for validating cell transplantation in spinal cord injuryDOI 10.1101/2024.01.29.577615Read

Neuromesodermal Progenitors Advance Network Formation of Spinal Neurons and Support Cells in Neural Ribbons <i>In Vitro</i> and Unprotected Survival in a Rat Subacute Contusion ModelSemantic proximity Read

Expandable and Rapidly Differentiating Human Induced Neural Stem Cell Lines for Multiple Tissue Engineering Applications.Semantic proximity Read

HiPSC-Derived NSCs Effectively Promote The Functional Recovery of Acute Spinal Cord Injury in MiceSemantic proximity Read

Stem cells for spinal cord injury: Strategies to inform differentiation and transplantationSemantic proximity Read

Generation of UCiPSCs-derived neurospheres for cell therapy and its applicationSemantic proximity Read

Analysis of astrocyte progenitors derived from human induced pluripotent stem cells <i>in vitro</i> and following transplantation into the intact spinal cordSemantic proximity Read

Human embryonic stem cell cultivation: historical perspective and evolution of xeno-free culture systemsSemantic proximity Read

Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells.Semantic proximity Read

Ascorbic Acid Can Promote the Generation and Expansion of Neuroepithelial-Like Stem Cells Derived from HiPS/ES Cells Under Chemically Defined Conditions Through Promoting Collagen SynthesisSemantic proximity Read

Mouse brain organoids model <i>in vivo</i> neurodevelopment and function and capture differences to humanSemantic proximity Read

Injury to the Spinal Cord Niche Alters the Engraftment Dynamics of Human Neural Stem CellsSemantic proximity Read

Rapid and efficient generation of human oligodendrocytes myelinating adult human cortical neuronsSemantic proximity Read