Article

Targeting NRAS Inhibits Cancer Cell Growth and Enhances Paclitaxel Sensitivity in Lung Adenocarcinoma

2024-04-30

Abstract excerpt

<title>Abstract</title> <p>Lung adenocarcinoma (LUAD)poses substantial therapeutic complexities due to its resistance to first-line chemotherapic agents such as paclitaxel. This study investigated the involvement of NRAS in the development of paclitaxel resistance in LUAD. We integrated transcriptome data from TCGA and other databases while conducting in vitro experiments We also used GSEA to identify NRAS-relate...

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Literature Corpus work: 3f8e74ad-4035-5e63-88cf-146bc76c18f4
DOI: 10.21203/rs.3.rs-4306414/v1

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