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Therapeutic and Prognostic Potential of G Protein‐Coupled Receptors in Lung Adenocarcinoma: Evidence From Transcriptome Data and In Vitro Experiments

1 May 2025

Abstract excerpt

BACKGROUND: G protein-coupled receptors (GPCRs), the largest family of cell-surface molecules involve in various signal transduction, have recently been recognized as important drivers of cancer. However, few studies have reported on the potential of GPCRs as therapeutic targets or biomarkers in lung adenocarcinoma (LUAD). METHODS: The expression profiles and clinical data of LUAD in the GSE30219 and GSE18842...

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PMID: 40364562
DOI: 10.1111/crj.70080

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