Article

FOXO3a shRNA and simultaneous induction of P27Kip1gene Inhibit the Breast Cancer Growth in Nude Mice

2020-06-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: FOXO proteins, which are overexpressed in multiple human tumors, belong to the Forkhead family of transcription factors that are involved in cell-cycle regulation, cell apoptosis, differentiation, stress response, and metabolism. The <italic>p27Kip1</italic> gene leads to cell cycle arrest, cell apoptosis, tumor suppressor genes, and cell adhesion. The low expre...

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Literature Corpus work: 3f6a1f0d-66ee-50b6-b2f4-004d6bb5d317
DOI: 10.21203/rs.3.rs-31573/v1

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