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Article

FOXO Signaling Pathways as Therapeutic Targets in Cancer

1 Jan 2017

Abstract excerpt

Many transcription factors play a key role in cellular differentiation and the delineation of cell phenotype. Transcription factors are regulated by phosphorylation, ubiquitination, acetylation/deacetylation and interactions between two or more proteins controlling multiple signaling pathways. These pathways regulate different physiological processes and pathological events, such as cancer and other diseases. The...

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PMID: 28808415
DOI: 10.7150/ijbs.20052

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