Article
Identification of essential genes of Pseudomonas aeruginosa for its growth in airway mucus.
Journal of microbiology (Seoul, Korea) - 1 Jan 2017
Alrahman Mohammed Abd, Yoon Sang Sun
Abstract excerpt
Pseudomonas aeruginosa has been identified as an important causative agent of airway infection, mainly in cystic fibrosis. This disease is characterized by defective mucociliary clearance induced in part by mucus hyper-production. Mucin is a major component of airway mucus and is heavily O-glycosylated, with a protein backbone. Airway infection is known to be established with bacterial adhesion to mucin. However,...
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