Article

RFMix-reader: Accelerated reading and processing for local ancestry studies

2024-07-17

Abstract excerpt

<h4>Motivation</h4> Local ancestry inference is a powerful technique in genetics, revealing population history and the genetic basis of diseases. It is particularly valuable for improving eQTL discovery and fine-mapping in admixed populations. Despite the widespread use of the RFMix software for local ancestry inference, large-scale genomic studies face challenges of high memory consumption and processing times...

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Literature Corpus work: 3f2ddcb7-175d-5456-81fe-c5cf1938befa
DOI: 10.1101/2024.07.13.603370

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