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The placenta goes viral: Retroviruses control gene expression in pregnancy

9 Oct 2018

Abstract excerpt

The co-option of endogenous retroviruses (ERVs) is increasingly recognized as a recurrent theme in placental biology, which has far-reaching implications for our understanding of mammalian evolution and reproductive health. Most research in this area has focused on ERV-derived proteins, which have been repeatedly co-opted to promote cell-cell fusion and immune modulation in the placenta. ERVs also harbor...

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PMID: 30300353
DOI: 10.1371/journal.pbio.3000028

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