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Article

Subtype-specific causal effects of hypothyroidism on obstructive sleep apnea: A bidirectional Mendelian randomization study

4 Jul 2025

Abstract excerpt

This study investigates the subtype-specific causal relationships between hypothyroidism (HT) and obstructive sleep apnea (OSA) using a bidirectional Mendelian randomization (MR) design. A two-sample MR analysis was conducted based on genome-wide association study summary statistics from European populations, including multiple HT subtypes and thyroid function indicators. The inverse variance weighted method was...

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PMID: 40629611
DOI: 10.1097/md.0000000000043266

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