Article

Effective QTL Discovery Incorporating Genomic Annotations

2015-11-16

Abstract excerpt

Mapping molecular QTLs has emerged as an important tool for understanding the genetic basis of cell functions. With the increasing availability of functional genomic data, it is natural to incorporate genomic annotations into QTL discovery. In this paper, we describe a novel method, named TORUS, for integrative QTL discovery. Using hierarchical modeling, our approach embeds a rigorous enrichment analysis to quanti...

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Literature Corpus work: 3eeac3c6-7775-564c-acca-8323882f8e81
DOI: 10.1101/032003

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