Article
Efficient Integrative Multi-SNP Association Analysis via Deterministic Approximation of Posteriors.
American journal of human genetics - 2 Jun 2016
Wen Xiaoquan, Lee Yeji, Luca Francesca, Pique-Regi Roger
Abstract excerpt
With the increasing availability of functional genomic data, incorporating genomic annotations into genetic association analysis has become a standard procedure. However, the existing methods often lack rigor and/or computational efficiency and consequently do not maximize the utility of functional annotations. In this paper, we propose a rigorous inference procedure to perform integrative association analysis...
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