Article

Diseased skin dermal proteomic profiles reflect shared extracellular matrix dysregulation patterns

2024-08-28

Abstract excerpt

<h4>ABSTRACT</h4> Extracellular matrix (ECM) plays a major role in the maintenance of skin homeostasis and modifications in its structure are commonly linked with skin diseases of different origins. Recent evidence shows that epidermal fibroblasts can be important regulators of epidermal pathology. However, despite recent advances, the intricate mechanisms responsible for the ECM defects in a wide range of skin p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ee820a4-42e6-5ffb-97af-574fe44190bf
DOI: 10.1101/2024.08.27.609987

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Diseased skin dermal proteomic profiles reflect shared extracellular matrix dysregulation patternsDOI 10.1101/2024.08.27.609987Read

Spatially and cell-type resolved quantitative proteomic atlas of healthy human skinSemantic proximity Read

Therapies for genetic extracellular matrix diseases of the skin.Semantic proximity Read

Global remodelling of cellular microenvironment due to loss of collagen VIISemantic proximity Read

Review—Current Concepts in Inflammatory Skin Diseases Evolved by Transcriptome Analysis: In-Depth Analysis of Atopic Dermatitis and PsoriasisSemantic proximity Read

Unravelling drivers of cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.Semantic proximity Read

Cartilage-like composition of keloid scar extracellular matrix suggests fibroblast mis-differentiation in diseaseSemantic proximity Read

Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes.Semantic proximity Read

Advancements in Early Diagnosis and Personalized Treatment Strategies for Skin Diseases: A Meta-Analysis of Interdisciplinary Approaches Combining Dermatology, Genetics, and ImmunologySemantic proximity Read

Multiomics Integration in Skin Diseases with Alterations in Notch Signaling Pathway: PlatOMICs Phase 1 Deployment.Semantic proximity Read

Identification of biological processes and potential inhibitors for aging skinSemantic proximity Read

Disorders of the cutaneous basement membrane zone--the paradigm of epidermolysis bullosa.Semantic proximity Read

Proteomic anatomy of human skinSemantic proximity Read