Article
Cartilage-like composition of keloid scar extracellular matrix suggests fibroblast mis-differentiation in disease
1 Nov 2019
Abstract excerpt
Following wound damage to the skin, the scarring spectrum is wide-ranging, from a manageable normal scar through to pathological keloids. The question remains whether these fibrotic lesions represent simply a quantitative extreme, or alternatively, whether they are qualitatively distinct. A three-way comparison of the extracellular matrix (ECM) composition of normal skin, normal scar and keloids was performed...
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