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Article

Therapies for genetic extracellular matrix diseases of the skin.

Matrix biology : journal of the International Society for Matrix Biology - 1 Oct 2018

Nyström Alexander, Bernasconi Rocco, Bornert Olivier

Abstract excerpt

A specialized, highly developed dermal extracellular matrix (ECM) provides the skin with its unique mechano-resilient properties and is vital for organ function. Accordingly, genetically acquired deficiency of dermal ECM proteins or proteins essential for the post-translational modification and homeostasis of the dermal ECM, results in diseases affecting the skin. Some of these diseases are lethal or lead to...

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Identifiers

PMID: 29274938
DOI: 10.1016/j.matbio.2017.12.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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