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Article

Global remodelling of cellular microenvironment due to loss of collagen VII

16 Apr 2013

Abstract excerpt

The mammalian cellular microenvironment is shaped by soluble factors and structural components, the extracellular matrix, providing physical support, regulating adhesion and signalling. A global, quantitative mass spectrometry strategy, combined with bioinformatics data processing, was developed to assess proteome differences in the microenvironment of primary human fibroblasts. We studied secreted proteins of...

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Identifiers

PMID: 23591773
DOI: 10.1038/msb.2013.17

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