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Microglia Morphological Response to Mesenchymal Stromal Cell Extracellular Vesicles Demonstrates EV Therapeutic Potential for Modulating Neuroinflammation

2024-07-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Mesenchymal stromal cell derived extracellular vesicles (MSC-EVs) are a promising therapeutic for neuroinflammation. MSC-EVs can interact with microglia, the resident immune cells of the brain, to exert their immunomodulatory effects. In response to inflammatory cues, such as cytokines, microglia undergo phenotypic changes indicative of their function e.g. morphology and sec...

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Literature Corpus work
3ee41ae4-1e79-58d1-8211-656feec238f2
DOI
10.1101/2024.07.01.601612
Open publication

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