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Development of a High-throughput Morphological Assay for Evaluating Mesenchymal Stromal Cell-derived Extracellular Vesicle Modulation of Brain Pericyte Secretory Phenotype

2025-01-19

Abstract excerpt

<h4>ABSTRACT</h4> Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are a promising therapeutic tool for treating many neurodegenerative diseases. Neuroinflammation plays a major role in many of these conditions through an orchestration of interdependent processes that lead to the breakdown of the blood-brain barrier (BBB), infiltration of immune cells and neuronal death. MSC-EVs have shown prelim...

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Literature Corpus work
44b5dc5b-6e75-5b88-8996-d77dc8cc6c88
DOI
10.1101/2025.01.15.633196
Open publication

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Development of a High-throughput Morphological Assay for Evaluating Mesenchymal Stromal Cell-derived Extracellular Vesicle Modulation of Brain Pericyte Secretory PhenotypeDOI 10.1101/2025.01.15.633196
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