Article
Machine learning to detect Alzheimer’s disease from circulating non-coding RNAs
2019-05-14
Abstract excerpt
<h4>Background</h4> To develop therapeutics for Alzheimer’s disease, early detection of patients awakes new hope. Circulating small non-coding RNAs are among the prominent candidates for a blood-based diagnosis, requiring however growing cohort sizes. <h4>Methods</h4> We determined abundance levels of 21 known circulating microRNAs in 465 individuals encompassing Alzheimer’s patients and controls recruited in US...
Topics
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- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
Identifiers and source
- Literature Corpus work
- 423a6b6f-8db0-5835-856a-ed1bee672c85
- DOI
- 10.1101/638213
