HapCHAT: Adaptive haplotype assembly for efficiently leveraging high coverage in long reads

Abstract excerpt

<h4>Background</h4> Haplotype assembly is the process of assigning the different alleles of the variants covered by mapped sequencing reads to the two haplotypes of the genome of a human individual. Long reads, which are nowadays cheaper to produce and more widely available than ever before, have been used to reduce the fragmentation of the assembled haplotypes since their ability to span several variants along t...

Topics

Open a Topic to create a Post that cites this publication.

• Algorithms
• Diploidy
• Genome, Human
• Haplotypes
• High-Throughput Nucleotide Sequencing
• Polymorphism, Single Nucleotide
• Sequence Analysis, DNA
• Software

Identifiers and source

Literature Corpus work

4609e1d0-5c0c-5ba3-a2e8-219a1c7e989f

DOI

10.1101/170225