Article

Deciphering sex-specific genetic architectures using local Bayesian regressions

2019-05-31

Abstract excerpt

Many complex human traits exhibit differences between sexes. While numerous factors likely contribute to this phenomenon, growing evidence from genome-wide studies suggest a partial explanation: that males and females from the same population possess differing genetic architectures. Despite this, mapping gene-by-sex (G×S) interactions remains a challenge likely because the magnitude of such an interaction is typic...

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Literature Corpus work: 3e18a2fa-9a70-53a8-b440-90323a896023
DOI: 10.1101/653386

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