Article
Deciphering Sex-Specific Genetic Architectures Using Local Bayesian Regressions.
Genetics - 1 May 2020
Funkhouser Scott A, Vazquez Ana I, Steibel Juan P, Ernst Catherine W, Los Campos Gustavo de
Abstract excerpt
Many complex human traits exhibit differences between sexes. While numerous factors likely contribute to this phenomenon, growing evidence from genome-wide studies suggest a partial explanation: that males and females from the same population possess differing genetic architectures. Despite this, mapping gene-by-sex (G×S) interactions remains a challenge likely because the magnitude of such an interaction is...
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