Article

Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF and RA signaling pathways

2020-06-17

Abstract excerpt

<h4>Background: </h4> Biological pacemakers derived from pluripotent stem cell (PSC) have been considered as a potential therapeutic surrogate for sick sinus syndrome. So it’s essential to develop high efficient strategies for enrichment of sinoatrial node-like cells (SANLC) as seed cells for biological pacemakers. It has been reported that BMP, FGF and RA signaling pathways are involved in specification of differ...

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Literature Corpus work: 3e0117e5-b91b-5559-9ea9-0eec04cfc098
DOI: 10.21203/rs.2.23881/v3

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