Article
Differentiation of pluripotent embryonic stem cells into cardiomyocytes.
Circulation research - 9 Aug 2002
Boheler Kenneth R, Czyz Jaroslaw, Tweedie David, Yang Huang-Tian, Anisimov Sergey V, Wobus Anna M
Abstract excerpt
Embryonic stem (ES) cells have been established as permanent lines of undifferentiated pluripotent cells from early mouse embryos. ES cells provide a unique system for the genetic manipulation and the creation of knockout strains of mice through gene targeting. By cultivation in vitro as 3D aggregates called embryoid bodies, ES cells can differentiate into derivatives of all 3 primary germ layers, including...
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