Article
Generation of cardiac pacemaker cells by programming and differentiation.
Biochimica et biophysica acta - 1 Jul 2016
Husse Britta, Franz Wolfgang-Michael
Abstract excerpt
A number of diseases are caused by faulty function of the cardiac pacemaker and described as "sick sinus syndrome". The medical treatment of sick sinus syndrome with electrical pacemaker implants in the diseased heart includes risks. These problems may be overcome via "biological pacemaker" derived from different adult cardiac cells or pluripotent stem cells. The generation of cardiac pacemaker cells requires the...
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