Article

Detection of disease-specific signatures in B cell repertoires of lymphomas using machine learning

2023-10-10

Abstract excerpt

The classification of B cell lymphomas - mainly based on light microscopy evaluation by a pathologist - requires many years of training. Since the B cell receptor (BCR) of the lymphoma clonotype and the microenvironmental immune architecture are important features discriminating different lymphoma subsets, we asked whether BCR repertoire next-generation sequencing (NGS) of lymphoma-infiltrated tissues in conjuncti...

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Literature Corpus work: 3de140a6-0923-5c40-b7a1-42e36f878037
DOI: 10.1101/2023.10.05.561150

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