Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The T-cell Receptor Repertoire Influences the Tumor Microenvironment and Is Associated with Survival in Aggressive B-cell Lymphoma

20 Sept 2016

Abstract excerpt

Abstract Purpose: To investigate the relationship between the intra-tumoral T-cell receptor (TCR) repertoire and the tumor microenvironment (TME) in de novo diffuse large B-cell lymphoma (DLBCL) and the impact of TCR on survival. Experimental Design: We performed high-throughput unbiased TCRβ sequencing on a population-based cohort of 92 patients with DLBCL treated with conventional (i.e., non-checkpoint...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to CAR-T cell therapy research
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27649554
DOI: 10.1158/1078-0432.ccr-16-1576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The T-cell Receptor Repertoire Influences the Tumor Microenvironment and Is Associated with Survival in Aggressive B-cell LymphomaPMID 27649554Read ↗

Single-Cell RNA-Seq and Bulk RNA-Seq Reveal Intratumoral Heterogeneity and Tumor Microenvironment Characteristics in Diffuse Large B-Cell LymphomaSemantic proximity Read ↗

Characteristics of profiling the peripheral blood T‐cell receptor repertoire in patients with diffuse large B-cell lymphomaSemantic proximity Read ↗

Integrative genomic analysis identifies unique immune environments associated with immunotherapy response in diffuse large B cell lymphomaSemantic proximity Read ↗

Molecular complexity of diffuse large B-cell lymphoma: a molecular perspective and therapeutic implications.Semantic proximity Read ↗

Single-Cell Transcriptome Analysis Reveals Disease-Defining T-cell Subsets in the Tumor Microenvironment of Classic Hodgkin LymphomaSemantic proximity Read ↗

Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series.Semantic proximity Read ↗

The Diagnostic, Prognostic, and Therapeutic Potential of Adaptive Immune Receptor Repertoire Profiling in CancerSemantic proximity Read ↗

Single-cell landscape of primary central nervous system diffuse large B-cell lymphomaSemantic proximity Read ↗

PD-L1 gene alterations identify a subset of diffuse large B-cell lymphoma harboring a T-cell–inflamed phenotypeSemantic proximity Read ↗

Immune microenvironment subtypes and association with tumor cell mutations and antigen expression in follicular lymphomaSemantic proximity Read ↗

Comparative Profiling of TCR Repertoires in Extranodal NK/T-Cell Lymphoma and Healthy Individuals Highlights Unique Clonal Expansions and Potential Diagnostic BiomarkersSemantic proximity Read ↗

A Germinal Center-Associated Microenvironmental Signature Reflects Malignant Phenotype and Outcome of Diffuse Large B-cell LymphomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.