Article

Nasally-delivered interferon-λ protects mice against upper and lower respiratory tract infection of SARS-CoV-2 variants including Omicron

2022-01-24

Abstract excerpt

<h4>SUMMARY</h4> Although vaccines and monoclonal antibody countermeasures have reduced the morbidity and mortality associated with SARS-CoV-2 infection, variants with constellations of mutations in the spike gene threaten their efficacy. Accordingly, antiviral interventions that are resistant to further virus evolution are needed. The host-derived cytokine IFN-λ has been proposed as a possible treatment based on...

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Literature Corpus work: 3d54ebb3-9b3b-5ebe-9090-bdcfeb1e4730
DOI: 10.1101/2022.01.21.477296

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