Article

Znrf2-mediated Ubiquitination of ST2L Regulates Cardiac Fibrosis and Remodeling after Myocardial Infarction

2024-11-08

Abstract excerpt

<title>Abstract</title> <p>Myocardial infarction (MI) is a leading cause of cardiac death, primarily driven by myocardial necrosis resulting from coronary artery occlusion. Post-MI, ventricular remodeling, characterized by excessive extracellular matrix deposition, frequently progresses to heart failure. The IL-33/ST2L signaling axis is known for its protective role in mitigating fibrosis following MI. However, t...

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Literature Corpus work: 3d4fdd0a-4e05-5f46-898d-2fdb87874de8
DOI: 10.21203/rs.3.rs-5230050/v1

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