Article
Integrative scRNA-seq and spatial transcriptomics uncovers distinct macrophage-fibroblast cross-talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis
2024-12-11
Abstract excerpt
<h4>ABSTRACT</h4> Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell-cell interactions between patients with FAI and hip OA. In the current study, by using integrative single-cell RNA sequencing (scRN...
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Identifiers and source
- Literature Corpus work
- 3d24ed1b-ea03-5659-8514-7008ab461077
- DOI
- 10.1101/2024.12.09.627061
